Skip to content

Products and Contract Services

IVIS® Lumina

Overview


Sign up for our IVIS User Group Meeting on Tuesday, September 9th and Wednesday, September 10th in Nice, France (in conjunction with SMI)! 




The IVIS® Lumina from Caliper Life Sciences is an affordable, highly sensitive imaging system that offers users the flexibility to image fluorescent and/or bioluminescent reporters both in vivo and in vitro. It relies on Xenogen’s novel patented optical imaging technologies to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals. 

This user-friendly system includes a highly sensitive CCD camera, a light-tight imaging chamber with complete computer automation, and the Living Image® software package for image acquisition and analysis. An adjustable field of view from 5–12.5 cm allows imaging of up to 3 mice or a medium size rat and also accommodates standard microtiter plates for in vitro imaging. The system includes premium animal handling features such as a heated sample shelf, gas anesthesia connections and manifold, and an optional full gas anesthesia system.

For more information in our IVIS® Lumina Series imaging system please click the button below and complete our product & services inquiry form. 

Request a Quote

or contact David.Panzarella@caliperls.com




Applications

• Oncology Research (pdf)
• Infectious Disease (pdf)
• Inflammation (pdf)
• Metabolic Diseases (pdf)
• Neurology 
• Gene Therapy (pdf)
• Stem cell Biology
• Cardiovascular Disease (pdf)
• Immunology & Transplantation Biology
• Toxicology (pdf)
• Drug Metabolism Studies (pdf)

Features

• High-sensitivity in vivo and in vitro imaging of fluorescence and bioluminescence
• Adjustable field of view from 5 - 12.5 cm (for up to 3 mice or a medium sized rat)
• Camera CCD provides high quantum efficiency over the entire visible to near-infrared spectrum and is thermo-electrically (Peltier) cooled to -90 C to ensure low dark current and low noise.
• Light-tight imaging chamber
• 8 position emission filter wheel and 12 position excitation filter wheel
     • A set of four filter pairs for fluorescent imaging come standard with the instrument, in addition to a set of four background filters for subtraction of tissue autofluorescence.
• Heated stage to maintain optimum body temperature
• Motor controlled stage, filter wheel, lens position, and f-stop
• NIST traceable absolute calibrations
• Gas anesthesia inlet and outlet ports

Demos

Our product can be demonstrated at our facility in Hopkinton, Massachussetts or other Caliper Life Sciences offices worldwide.  Please contact your local Caliper Representative to arrange a demo.

Specifications

Power Requirements
6 Amps at 120V

Dimensions
•Imaging Chamber Interior Size: 43 x 38 x 43 cm (W x D x H) •Imaging System Space Requirement: 48 x 71 x 104 cm (W x D x H)

Camera Sensor
Back-thinned, back-illuminated Grade 1 CCD

CCD
Size 1.33 x 1.33 cm
Operating Temperature -90°C

Imaging Pixels
1024 x 1024

Quantum Efficiency
>85% 500 – 700 nm; >30% 400 – 900nm

Pixel Size
13 micron square

Minimum Detectable Radiance
100 photons/s/sr/cm2 (bin = 16, 5 min. exposure, f/1)

Field of View (FOV)
Minimum FOV 5 x 7.5 cm
Maximum FOV 10 x 12.5 cm

Minimum Image Pixel Resolution
100 microns (FOV = 5 cm, f/4)

Read Noise
< 3 electrons for bin=1,2,4; < 5 electrons for bin=8,16

Dark Current (Typical)
<120 electrons/s/cm2 or 2 x 10-4 electrons/s/pixel

Fluorescence Filters
Excitation 12
Emission 8

Computer
2.8 GHz, 1 GB RAM, RW CD/DVD, 80 GB HD, 20” flat screen monitor

Lens
f/0.95 – f/16, 50 mm

Stage Temperature
20 – 40°C